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EPRINEX® Multi Pour-On

EPRINEX Multi Pour-On was launched in 2017 and is licensed to treat dairying sheep and goats in addition to cattle. It was developed as a line extension of EPRINEX Pour-On, which was the first dairy and beef eprinomectin wormer with zero-milk withhold launched over 20 years ago.

Available in: 1L, 2.5L and 5L

eprinexmulti

Treats and Controls

http://www.cattleandsheepworming.com/en-ie/worms/lung-worm-dictyocaulus-viviparusTarget species - beef and dairy cattle

 

Target species - goats and sheep

  • Effective against the adult stages of many important gastrointestinal parasites of sheep and goats including:
    • Teladorsagia circumcincta (pinnata/trifurcata)
    • Haemonchus contortus
    • Trichostrongylus axei
    • Trichostrongylus colubriformis
    • Nematodirus battus 
    • Cooperia curticei
    • Oesophagostomum venulosum
    • Adult stage of the lungworm Dictyocaulus filaria

Features and Benefits

Target species - beef and dairy cattle

  • Zero milk withhold for any stage of pregnancy and lactation
  • Proven to overcome the production limiting effects of gutworm burdens1
    • Cows eat up to an extra 1kg dry matter per day2
    • Delivers increased milk yield of up to 2L per cow per day3
    • Improvements in fertility including shorter calving to conception intervals and higher pregnancy rates4
  • Weather-fast formulation5

 

Target species - goats and sheep

  • First licensed zero milk withdrawal pour-on worm control product available 
  • Treatment of sheep during the periparturient period effectively controlled gastro-intestinal nematode burdens and treated sheep produced over 10L more milk during the first 84 days of lactation than controls6

Cattle: 1ml/10kg

Sheep and Goats: 2ml/10kg

These tables are included as a guide - cattle, sheep and goats that fall between the weights listed should have their dose calculated appropriately.

EPRINEX Multi Pour-On Dose Guide for Cattle

   

Number of treatments per pack

Bodyweight

Dose 

1L

2.5L

5L

200kg

20ml

50

125

250

300kg

30ml

33

83

166

400kg

40ml

25

62

125

500kg

50ml

20

50

100

600kg

60ml

16

41

83

700kg

70ml

14

35

71

800kg

80ml

12

31

62

 

EPRINEX Multi Pour-On Dose Guide for Sheep & Goats

   

Number of treatments per pack

Bodyweight

Dose 

1L

2.5L

5L

10kg

2ml

500

1250

2500

20kg

4ml

250

624

1250

30kg

6ml

166

416

833

40kg

8ml

125

312

625

50kg

10ml

100

250

500

60kg

12ml

83

208

416

70kg

14ml

71

178

357

80kg

16ml

62

156

312

Cattle:

Meat and offal: 15 days.

Milk: zero hours.

Sheep:

Meat and offal: 2 days

Milk: zero hours

Goats:

Meat and offal: 1 day

Milk: zero hours

Cattle: Should be applied topically by pouring along the backline in a narrow strip extending from the withers to the tailhead.

Sheep: When administering the product along the backline, part the fleece/coat and place applicator nozzle or bottle spout against the skin.

 

How to apply EPRINEX Multi Pour-on

References
  1. Studies carried out using EPRINEX Pour-on for Beef and Dairy Cattle (Eprinomectin), which has the same formulation as EPRINEX Multi Pour-On 5mg/ml, see HPRA, (2018) IPAR EPRINEX Multi Pour-On 5 mg/ml pour-on for beef and dairy cattle, sheep and goats [online] Available at: https://www.hpra.ie/img/uploaded/swedocuments/Public_AR_VPA10454-034-001_07122018154613.pdf [Accessed 18 Feb 2019]
  2. Forbes et al. (2004) Veterinary Parasitology 125:353-364
  3. McPherson WB et al. (2001) New Zealand Veterinary Journal 49:106-110
  4. McPherson WB et al. (1999) Proc AAVP, New Orleans
  5. Gogolewski et al. (1997) Parasitology 69:95-102
  6. Papadopoulous et al (2016), WBC Dublin Abstract No 1561

EPRINEX Multi Pour-On

Frequently Asked Questions

Yes EPRINEX Multi Pour-On can be used in lactating cows and has a zero milk withdrawal so can be used at any stage of lactation.

EPRINEX Multi should be applied along the backline in a narrow strip extending from the withers to the tailhead. The dose should be measured using the measuring cup supplied or using an appropriate applicator gun. It is recommended to double check the calibration of these every time you apply the product.

Treatment around the time of calving will remove a cow’s gut worm burden and protect against re-infection during early lactation, optimising feed intake and energy balance during the transition period. The lactation-long benefits of removing gut worm at this time have been demonstrated, with cows shown to produce up to 2 litres more milk each day for the entire lactation1,2.

References
1. Reist, M., Forbes, A.B., Bonfanti, M., Beretta, W., Pfister, K., 2011, The effect of eprinomectin treatment on milk yield and quality in dairy cows in South Tyrol as related to gastro-intestinal nematodes. Vet Rec 168 : 484

2. Studies carried out using Eprinex Pour-on for Beef and Dairy Cattle (Eprinomectin), which has the same formulation as Eprinex Multi 5mg/ml, see HPRA, (2018) IPAR Eprinex Multi 5 mg/ml pour-on for beef
and dairy cattle, sheep and goats [online] Available at: https://www. hpra.ie/img/uploaded/swedocuments/Public_AR_VPA10454-034
001_07122018154613.pdf [Accessed 18 Feb 2019]

Whilst all efforts should be taken to treat cattle under optimal conditions, clinical evidence has demonstrated that EPRINEX Multi Pour-On is rainfast. In cattle, rainfall before, during or after the application of the product has been shown to have no impact on its efficacy. It has also been demonstrated that haircoat length has no impact on the product’s efficacy1,2.

 

References: 

1. Studies carried out using Eprinex Pour-on for Beef and Dairy Cattle
(Eprinomectin), which has the same formulation as Eprinex Multi 5mg/ml, see HPRA, (2018) IPAR Eprinex Multi 5 mg/ml pour-on for beef
and dairy cattle, sheep and goats [online] Available at: https://www. hpra.ie/img/uploaded/swedocuments/Public_AR_VPA10454-034
001_07122018154613.pdf [Accessed 18 Feb 2019]
2. Gogolewski et al. (1997) Veterinary Parasitology 69:95-102

The MOO Test (Milk Ostertagia ostertagi ELISA) is a useful diagnostic tool in dairy herds. Where the level of exposure is determined to be high, Ostertagia is likely to be having a significant impact on productivity, and treatment of the herd is likely to yield an improvement in milk production.