Frequently Asked Questions


Yes EPRINEX Pour-On can be used in lactating cows and has a zero milk withdrawal so can be used at any stage of lactation.

EPRINEX Pour-On should be applied along the backline in a narrow strip extending from the withers to the tailhead. The dose should be measured using the measuring cup supplied or using an appropriate applicator gun. It is recommended to double check the calibration of these every time you apply the product.

Treatment around the time of calving will remove a cow’s gut worm burden and protect against re-infection during early lactation, optimising feed intake and energy balance during the transition period. The lactation-long benefits of removing gut worm at this time have been demonstrated, with cows shown to produce up to a litre or more milk each day for the entire lactation1.

Whilst care should be taken to ensure that cattle are treated in optimal conditions, there is evidence to show that EPRINEX Pour-On is rainfast. In cattle, rainfall before or after the application of the product has been shown to have no impact on its efficacy2. It has also been demonstrated that haircoat length has no impact on the product’s efficacy2.

The MOO Test (Milk Ostertagia ostertagi ELISA) is a useful diagnostic tool in dairy herds and can be performed on a bulk milk sample. Where the level of exposure is determined to be high, Ostertagia is likely to be having a significant impact on productivity, and treatment of the herd is likely to yield an improvement in milk production.


The product can be administered to beef cows at any stage of pregnancy or lactation. Dairy cows producing milk for human consumption should not be treated during lactation, or within 60 days of parturition. It will not affect the fertility of cows and bulls and can be given to all ages of animals including young calves.

Pour-on macrocyclic lactones such as IVOMEC Classic Pour-On and EPRINEX Pour-On treat and control both sucking and biting lice and chorioptic and sarcoptic mange mite infections. Injectable macrocyclic lactone products such as IVOMEC Classic Injection and IVOMEC Super treat and control sucking lice and burrowing mites, but may not fully eliminate infestations with biting lice and the surface feeding chorioptic mange mite.

When IVOMEC Classic Pour-On is applied at the recommended dosage of 1ml per 10kg bodyweight, it controls infections with Trichostrongylus axei and Cooperia spp acquired up to 14 days after treatment, Ostertagia ostertagi and Oesophagostomum radiatum acquired up to 21 days after treatment, and Dictyocaulus viviparus (lungworm) acquired up to 28 days after treatment. It also controls horn fly (Haematobia irritans) for up to 35 days after treatment.


IVOMEC Classic Injection for Cattle and Sheep should be given only by subcutaneous injection, using aseptic precautions, at the recommended dosage level of 1ml/50kg of bodyweight under the loose skin in front of, or behind, the shoulder in cattle and in the neck in sheep. Use of a sterile 17 gauge ½ inch (15-20 mm) needle is suggested.

Sheep scab (Psoroptes ovis) is an extremely contagious external parasite of sheep. To ensure complete control great care must be taken to avoid re-infestation, as mites may be viable for up to 15 days off the sheep. It is important that all sheep which have been in contact with infected sheep are treated. In sheep, treatment of psoroptic mange (sheep scab) with one injection is not recommended because, although clinical improvement may be seen, elimination of all mites may not occur. Two injections with a seven day interval are required.


IVOMEC Super should be administered only by subcutaneous injection at the recommended dosage level of 1 ml/50 kg bodyweight under the loose skin in front of, or behind, the shoulder. Divide doses greater than 10 ml between two injection sites. A sterile 17 gauge ½ inch (15-20 mm) needle is recommended. Replace with a fresh sterile needle after every 10-12 animals or sooner if the needle becomes soiled.

Mature fluke burdens have the greatest production impact on cattle. Removing fluke burdens at the end of the grazing period, as animals are housed, removes this productivity check. Research suggests that the majority (97%) of fluke carried by cattle by the time they are housed are late immature/adult stages3. Treating at housing with a flukicide effective against the later stages of fluke was to be used, such as IVOMEC Super Injection for Cattle which is effective against the mature stage of the parasite (from 12 weeks) will ensure that cattle are immediately able to maximise their growth from winter rations.  


Nitroxynil, the active ingredient of TRODAX has been shown to have full efficacy against triclabendazole-resistant liver fluke4. Nitroxynil is active against the late immature and adult stages of liver fluke. It does not treat the stage of fluke responsible for acute fluke disease, but provides an effective treatment option against the later stages for both cattle and sheep.


ORAMEC is suitable for use in all ages of sheep, including lambs.

Ewes may be treated at any stage of pregnancy, unless milk is intended for human consumption when animals should not be treated within 60 days prior to the start of lactation.


  1. Verschave et al (2014) BMC Vet Res 10; 264-272
  2. Gogolewski et al (1997) Vet Parasitol 69; 95-102
  3. MacGillivray et al (2011) Proc WAAVP, Argentina
  4. Hanna et al. (2015) Vet Parasitol 207; 34-43